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aβpp rabbit monoclonal antibody  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc aβpp rabbit monoclonal antibody
    Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.
    Aβpp Rabbit Monoclonal Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/a%CE%B2pp+rabbit+monoclonal+antibody/pmc12344242-68-5-14?v=Cell+Signaling+Technology+Inc
    Average 93 stars, based on 11 article reviews
    aβpp rabbit monoclonal antibody - by Bioz Stars, 2026-07
    93/100 stars

    Images

    1) Product Images from "Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease"

    Article Title: Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease

    Journal: Journal of Alzheimer's Disease Reports

    doi: 10.1177/25424823251358414

    Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.
    Figure Legend Snippet: Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.

    Techniques Used: Transgenic Assay, Control, Expressing

    Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of male rats. Sparse amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of male non-transgenic animals [M-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in male transgenic animals [M-TG; control diet or high fat diet (HFD)], (E-H) widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of images from n = 4 animals.
    Figure Legend Snippet: Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of male rats. Sparse amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of male non-transgenic animals [M-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in male transgenic animals [M-TG; control diet or high fat diet (HFD)], (E-H) widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of images from n = 4 animals.

    Techniques Used: Immunohistochemistry, Transgenic Assay, Control, Staining, Immunostaining

    Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of female rats. Very scant amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of female non-transgenic animals [F-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in female transgenic animals [F-TG; control diet or high fat diet (HFD)], (E-H), widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of image n = 4 in each experimental group.
    Figure Legend Snippet: Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of female rats. Very scant amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of female non-transgenic animals [F-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in female transgenic animals [F-TG; control diet or high fat diet (HFD)], (E-H), widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of image n = 4 in each experimental group.

    Techniques Used: Immunohistochemistry, Transgenic Assay, Control, Staining, Immunostaining



    Similar Products

    aβpp rabbit monoclonal antibody  (Cell Signaling Technology Inc)
    93
    Cell Signaling Technology Inc aβpp rabbit monoclonal antibody
    Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.
    Aβpp Rabbit Monoclonal Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/a%CE%B2pp+rabbit+monoclonal+antibody/pmc12344242-68-5-14?v=Cell+Signaling+Technology+Inc
    Average 93 stars, based on 1 article reviews
    aβpp rabbit monoclonal antibody - by Bioz Stars, 2026-07
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.

    Journal: Journal of Alzheimer's Disease Reports

    Article Title: Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease

    doi: 10.1177/25424823251358414

    Figure Lengend Snippet: Schematic diagram of the study design. Twelve-month-old male and female Wild-type [Fischer 344 (F344); WT] or the amyloid precursor protein/presenilin1 (APP/PS1)-overexpressing Transgenic (TG) rats were used in this study (n = 4 per experimental group). This schematic figure shows the experimental plan for the 12 months old WT and TG rats that were fed Control diet (CD) or high-fat diet (HFD) for following six months. At the end of six months rats were sacrificed, to assess the changes in the mRNA expression of Alzheimer's disease related genes in the ileal mucosa.

    Article Snippet: Sections were then incubated in AβPP rabbit monoclonal antibody (APP, E5X 2B, Cat# 2979, Cell Signaling Technology) at 1:200 dilution at room temperature for overnight.

    Techniques: Transgenic Assay, Control, Expressing

    Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of male rats. Sparse amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of male non-transgenic animals [M-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in male transgenic animals [M-TG; control diet or high fat diet (HFD)], (E-H) widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of images from n = 4 animals.

    Journal: Journal of Alzheimer's Disease Reports

    Article Title: Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease

    doi: 10.1177/25424823251358414

    Figure Lengend Snippet: Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of male rats. Sparse amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of male non-transgenic animals [M-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in male transgenic animals [M-TG; control diet or high fat diet (HFD)], (E-H) widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of images from n = 4 animals.

    Article Snippet: Sections were then incubated in AβPP rabbit monoclonal antibody (APP, E5X 2B, Cat# 2979, Cell Signaling Technology) at 1:200 dilution at room temperature for overnight.

    Techniques: Immunohistochemistry, Transgenic Assay, Control, Staining, Immunostaining

    Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of female rats. Very scant amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of female non-transgenic animals [F-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in female transgenic animals [F-TG; control diet or high fat diet (HFD)], (E-H), widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of image n = 4 in each experimental group.

    Journal: Journal of Alzheimer's Disease Reports

    Article Title: Potential link of high fat diet and mRNA expression of Alzheimer's disease-related genes in the enteric mucosa of a rat model of Alzheimer's disease

    doi: 10.1177/25424823251358414

    Figure Lengend Snippet: Demonstration of amyloid-β protein precursor immunohistochemistry in ileal mucosa of intestine tissue of female rats. Very scant amyloid-β protein precursor (AβPP) immunoreactivity [APP (E5X2B) Rabbit mAb that recognizes endogenous levels of human AβPP] was present in the intestine of female non-transgenic animals [F-NTG (or WT); control diet or high fat diet (HFD)] (A-D). However, in female transgenic animals [F-TG; control diet or high fat diet (HFD)], (E-H), widespread immuno-positive staining for AβPP is demonstrated in Auerbach's nerve plexus, located between longitudinal and circular smooth muscle layers of the intestinal wall, as well as multifocal staining in Meissner's nerve plexus, located in the submucosa. Bar magnification (A, C, E, G = 100 µm; B, D, F, H = 50 µm). Arrow indicates AβPP immunostaining in the nerve plexus. Each figure is representative of image n = 4 in each experimental group.

    Article Snippet: Sections were then incubated in AβPP rabbit monoclonal antibody (APP, E5X 2B, Cat# 2979, Cell Signaling Technology) at 1:200 dilution at room temperature for overnight.

    Techniques: Immunohistochemistry, Transgenic Assay, Control, Staining, Immunostaining